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Nutrition

Leucine

An essential amino acid that directly stimulates muscle protein synthesis.

Updated

Leucine is the most important amino acid for triggering muscle protein synthesis (MPS). It activates the mTOR pathway, the molecular switch for muscle building. Each meal should contain 2.5-3g of leucine to maximally stimulate MPS. This is why protein quality and leucine content matter, not just total protein.

Examples

  • 2.5-3g leucine needed to maximize MPS
  • 25g whey protein contains ~2.5g leucine
  • Triggers mTOR pathway for muscle growth

Common questions

What is Leucine?

An essential amino acid that directly stimulates muscle protein synthesis. Leucine is the most important amino acid for triggering muscle protein synthesis (MPS).

What are examples of Leucine?

2.5-3g leucine needed to maximize MPS; 25g whey protein contains ~2.5g leucine; Triggers mTOR pathway for muscle growth.

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